- All
- Product Name
- Product Keyword
- Product Model
- Product Summary
- Product Description
- Multi Field Search
 |
product description
Human Leukocyte Antigen -B27 (HLA-B27) gene is an allele for human primary tissue compatibility composite secretions (MHC,) i molecules in the I class, all of the human body Almost allocate in nuclear cells, which are especially rich in lymphocytes.
Studies have shown that ankylosing spondylitis (AS) is a chronic autoimmune disease associated with HLA-B27 genes, associated with genetic factors. According to data statistics, there are more than 4 million AS patients in my country, and more than 90% of patients with HLA-B27 antigens are positive, and only 5-10% of the ordinary population is positive. The most significant change in the disease is joint fibrosis and osteotropic. If you don't have timely diagnosis, it is easy to cause the patient's joint malformation, lifelong pain, so there is \"Undead cancer \". In addition, AS is similar to many disease symptoms and is difficult to diagnose, so HLA-B27 has an important clinical significance for early diagnosis, timely treatment and active prevention of AS.
The HLA-B27 nucleic acid test kit (fluorescent PCR method) developed by the company can detect B2702, B2704, B2705 gene as subtypes related to AS, which can determine the susceptible population of AS in a random population; for the history of AS family The population, HLA-B27 detection can be used as one of the early warning diagnosis of ankylosing spondylitis; and HLA-B27 detection can be used as an important aid for clinical diagnosis and differential diagnosis of clinical diagnosis and differential diagnosis.
At present, the clinical laboratory detects the expression antigen of the HLA-B27 gene by flow cellular technology to a largely increased sensitivity and specificity of detection, shorten the detection time, but due to instrument expensive, the operator and the sample to be inspected Quality requirements are highly issued, to some extent, limit the promotion and application of this technology. The fluorescent PCR method has an advantage of strong specificity, high sensitivity, and rapid. Provide possibilities for improving the accuracy and accuracy of HLA-B27 detection.
This kit is designed to participate in sample extraction, and the full enclosed reaction system can be realized to monitor the detection process, effectively prevent the occurrence of false negative, ensuring accurate and reliable detection results. Sample pre-processing with automated nucleic acid extractors and supporting extraction reagents, easy to operate, and can effectively reduce errors caused by manual operation.
Product parameters
Test method: use real-time fluorescent PCR technology, HLA-B27 gene (FAM channel), internal standard (HEX / VIC channel), dual channel detection
Product Specifications: 32 Test / Box
Sensitivity: 500COPIES / ML
Precision: Precision reference products (HLA-B2704), low (HLA-B2705) concentration, repeatedly tested 10 times, CT values (CV,%) ≤ 5%
Specificity: This kit and HLA-A1, HLA-DRB1, EB, HLA-B58, HLA-DQ, HLA-B8, HLA-DPB1, HLA-B2703, HLA-2707, B2709, B2711, B2706, etc. reaction
Validity: -20 ° C ± 5 ° C for 12 months
